Kidney Cancer

Kidney Cancer

 

Kidney cancer has historically been one of the most difficult cancers to treat. Research developments in immunotherapy and targeted treatments have resulted in advances that have helped patients live longer, higher-quality lives, including the development of several new drugs that target vulnerable pathways in cancer cells.

Survival rates for kidney cancer have improved steadily since the early 1980s. While they remain lower than other cancers, a wide range of research is underway to expand treatment options and improve the lives of patients with the disease.

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1996

New treatment techniques introduced for small renal tumors

New treatment techniques introduced for small renal tumors

New treatment approaches called cryoablation and radiofrequency ablation are introduced as alternatives to surgery. For both procedures, the doctor inserts a probe through a patient's skin into the renal tumor in order to kill the tumor through freezing (cryoablation) or use of an electric current (radiofrequency ablation). The long-term outcomes of these procedures are still being studied.

1992

First immunotherapy approved for kidney cancer

First immunotherapy approved for kidney cancer

The Food and Drug Administration approves interleukin-2 (IL-2), a drug that soon becomes standard therapy for advanced renal cell carcinoma. Decades later, IL-2 remains the only systemic treatment that has been shown to cure some patients with the disease. Yet less than 20 percent of patients respond to the treatment, and the need for more effective therapies remains urgent.

1991

Introduction of laparoscopic surgery minimizes pain, recovery time

Introduction of laparoscopic surgery minimizes pain, recovery time

Laparoscopic surgery for renal cancer – in which a surgeon makes several small incisions and uses telescoping equipment to remove the full kidney – emerges as an effective alternative to traditional open surgery through one larger incision. This new approach rapidly becomes the surgical standard, allowing patients to recover faster and experience less pain. Within the next few years, surgeons successfully apply laparoscopic techniques to partial nephrectomies, in which tumors are removed but healthy kidney tissue is left intact.

1985

Immunotherapy benefits patients with advanced renal cell carcinoma

1977

Removing just part of the cancerous kidney is proven safe and effective

Removing just part of the cancerous kidney is proven safe and effective

Studies indicate that some patients with early-stage malignant tumors in one or both kidneys are candidates for partial nephrectomy – surgery in which the tumor and only part of the kidney is removed, as opposed to removing the whole kidney. This refined approach revolutionizes treatment of such tumors, preserving patients' kidney function and helping many to avoid the difficult experience of long-term dialysis.

1963

First evidence that surgical removal of kidney is effective for early-stage cancer