Pediatric Cancer

Pediatric Cancer

Pediatric cancer care offers one of the most striking examples of progress in modern medicine. In the 1950s, less than 10 percent of children with cancer were cured. Today, nearly 80 percent will survive a cancer diagnosis.

Federally-funded clinical trials have been especially important in pediatric cancer. Most of today's effective treatments for childhood cancers were developed through trials conducted by the National Cancer Institute's Clinical Trials Cooperative Groups. Currently, 50 to 60 percent of eligible children with cancer are enrolled in these trials.

While overall progress has been impressive, some childhood cancers remain very difficult to treat, and one in five children ultimately does not survive. Continued research is essential to develop more effective, targeted, and safer treatments, so that even more children with cancer have the potential to live full and productive lives.

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1947

First-ever remission of pediatric leukemia

First-ever remission of pediatric leukemia

Badge indicating that research was paid for using federal funds

Sidney Farber, a physician at Children's Hospital Boston, achieves the first partial remission of pediatric leukemia in a 4-year-old girl using the drug aminopterin. He soon documents 10 cases of remission in a landmark scientific paper. Until this time, children with acute leukemia usually died within weeks of being diagnosed. While early remissions prove temporary, they pave the way for therapies that cure thousands of patients in the decades to come, allowing most childhood cancer patients to live long, healthy lives.