Testicular Cancer

Testicular Cancer

In the four decades since the first cure for advanced testicular cancer was reported by the National Cancer Institute, testicular cancer has emerged as one of the greatest success stories in cancer treatment. Modern therapies now cure 95 percent of men diagnosed with testicular cancer. Achievements in testicular cancer treatments were driven by clinical trials that provided critical insight on the most effective uses of chemotherapy, radiation and surgery. Studies have guided doctors as they increasingly adopt a "less is more" approach to cancer therapy: more than three-quarters of men with early-stage testicular cancer are now treated with surgery alone.

However, gaps in treatment and long-term care still exist. A small portion of patients – mostly young men – have cancers that do not respond to current therapies and there is a growing need for follow-up survivorship care to address any long-term health risks associated with the disease and treatment.

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2005

Testicular cancer survivors face increased risk of second cancers, other health problems

Testicular cancer survivors face increased risk of second cancers, other health problems

A major study finds that survivors of testicular cancer – especially those who received radiation or chemotherapy – have double the risk of developing a second cancer three or more decades after their initial diagnosis. Other research identifies an increased risk of cardiovascular disease and chronically low testosterone. These findings highlight the need for doctors to continually monitor for long-term health effects among the growing number of cancer survivors.

2004

Single dose of chemotherapy reduces risk of cancer recurrence in men with early-stage disease

Single dose of chemotherapy reduces risk of cancer recurrence in men with early-stage disease

A large European study shows that a single dose of the chemotherapy drug carboplatin (Paraplatin, Paraplat), following surgical removal of the cancerous testicle, lowers the risk of cancer recurrence and may reduce the risk of cancer developing in the opposite testicle. This finding results in a new treatment option for men with early-stage testicular cancer, potentially sparing them from standard radiation therapy, which is highly effective but is associated with an increased risk of developing a second cancer in another organ later in life.