Listed below are the current guidelines, provisional clinical opinions, endorsements, and updates in development. Topics prioritized for development by the Clinical Practice Guidelines Committee and Guideline Advisory Groups are listed by disease site. To submit a topic for consideration, take our survey. To learn more about the ASCO Guideline development process, access the Guideline Methodology page. If you are interested in guideline development, please visit the volunteer portal to express interest.

Guidelines/Provisional Clinical Opinions (PCOs)/Endorsements in Development



  • Neoadjuvant Therapy for Rectal Cancer
  • Systemic Therapy for Neuroendocrine Tumors
  • Targeted Therapy and Immunotherapy for Advanced Cholangiocarcinoma



  • NACT for Newly Diagnosed, Advanced Ovarian Cancer
  • The Role of Postoperative Radiation Therapy for Endometrial Cancer Endorsement
  • Treatment of Endometrial Cancer

Head and Neck

  • Immunotherapy and Biomarker Testing in Recurrent and Metastatic Head and Neck Cancers
  • Consideration of Dental Care and Osteonecrosis in Patients Treated with Radiotherapy for Head and Neck Cancer joint guideline with ISOO and MASCC
  • Transoral Robotic Surgery for Oropharynx Cancer: Optimizing Patient Selection in HPV+ Oropharyngeal Cancer and Use of Adjuvant Therapy




  • Metastatic Breast Cancer: Resource Stratified Guideline Adaptation

Supportive Care


  • Adolescent and Young Adult Survivorship
  • Management of Cancer During Pregnancy
  • Screening, Assessment, and Care of Anxiety and Depressive Symptoms in Adults with Cancer



Guideline Development Priorities 2022-2023

Breast Cancer

  • Endocrine Treatment and Targeted Therapy for Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer Update
  • Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer Update
  • Use of Endocrine Therapy for Breast Cancer Risk Reduction Update
  • Sentinel Lymph Node Biopsy for Patients with Early-Stage Breast Cancer Update
  • Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer Update

Gastrointestinal Cancer

  • Systemic Therapy (including Targeted Therapy) for Biliary Tract Cancer
  • Systemic Therapy for Advanced Hepatocellular Carcinoma Update
  • Perioperative Management of Gastric Cancer with Diagnostic Laparoscopy and Nodal Dissection and Pathology
  • Treatment Options for Locoregional and Metastatic Small Bowel/Ampullary Cancer
  • Treatment Options for Anal Cancer

Genitourinary Cancer

  • Post-Operative Radiotherapy After Prostatectomy Endorsement Update
  • Primary Tumor-Directed and Metastasis-Directed Local Therapy in Metastatic Prostate Cancer
  • Genitourinary Cancers Survivorship
  • Special Considerations for Elderly Patients with Genitourinary Cancers
  • Adjuvant Treatment of Localized and Oligometastatic Renal Cell Carcinoma After Definitive Therapy

Gynecologic Cancer

  • First Platinum-Sensitive Ovarian Cancer Recurrence
  • Gynecologic Cancers Survivorship
  • Treatment of Invasive Cervical Cancer
  • Recurrent Endometrial Cancer

Head and Neck Cancer

  • Use of Systemic Treatment in the Management of Advanced Thyroid Cancer
  • Management of Advanced Cutaneous Squamous Cell of the Head and Neck
  • Management of Locoregionally Recurrent Head and Neck Cancer
  • Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer
  • Management of Head and Neck Cancers in the Very Elderly (80+) and/or Frail Patient Population

Hematological Malignancies

  • Treatment of Multiple Myeloma Update
  • New Treatment of Newly Diagnosed Chronic Lymphocytic Leukemia
  • New Treatment of Aggressive Lymphomas with a Focus on B Cell Lymphoma
  • New Risk-Based Management of Myelodysplastic Syndromes


  • Systemic Therapy for Sarcoma
  • Treatment of Leptomeningeal Metastases
  • Treatment of Non-Melanoma Skin Cancer

Resource Stratified

  • Survivorship Care in Adolescents, Young Adults, and Adults
  • Geriatric Oncology
  • Treatment of Patients with Endometrial Cancer

Supportive Care

  • Integration of Patient-Reported Outcomes in Cancer Care
  • Management of Dermatologic Events from Cancer Treatment
  • Management of Treatment-Associated Interstitial Lung Disease
  • White Cell Growth Factors Update
  • Central Venous Catheter Care Update

Patient & Survivor Care

  • Management of Sleep Problems in Cancer Survivors
  • Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers Update
  • Survivorship After Stem Cell Transplantation

Thoracic Cancer

  • Molecular Testing for the Selection of Patients with Lung Cancer for Treatment with Targeted Tyrosine Kinase Inhibitors Guideline Endorsement Endorsement Update
  • Management of Stage I Non-Small Cell Lung Cancer
  • The Role of CT Screening for Lung Cancer in Clinical Practice Update
  • Duration of Systemic Therapy for Stage IV Lung Cancer
  • Management of Multifocal Lung Adenocarcinoma

Recently Published Guidelines

*Living Guideline