ASCO’s CancerLinQ and Owkin announced today a new research collaboration to use artificial intelligence to analyze real-world oncology data with the aim to understand why some cases of metastatic non-small cell lung cancer (NSCLC) are resistant to first-line immunotherapy treatment.
“The Association for Clinical Oncology (ASCO) applauds the Food and Drug Administration’s (FDA) decision to remove Juul products from the market in the United States (U.S.). This is an important step in preventing another generation from becoming addicted to nicotine—regardless of how it is delivered.”
One June 8, CancerLinQ® LLC and HealthVerity, Inc., today announced a collaboration that will create the nation’s premier real-world oncology data ecosystem to advance cancer care and research for government and public health agencies.
Based on guidance from biomarker screening, patients who are 55 years of age and older with low-grade luminal A-type breast cancer may only need endocrine therapy following breast conserving surgery and could avoid radiation therapy entirely, according to new research findings that will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
Two targeted therapies, dabrafenib (Taflinar®) plus trametinib (Mekinst®), significantly increased the overall response rate compared to the standard-of-care chemotherapy combination of carboplatin plus vincristine in pediatric patients with BRAF V600 mutation-positive low-grade gliomas. Secondary findings showed an improved clinical benefit rate and prolonged progression-free survival for dabrafenib plus trametinib compared to carboplatin plus vincristine, according to new research that will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
The use of panitumumab (Vectibix®) plus mFOLFOX6 significantly improved overall survival in patients with RAS wild-type metastatic colorectal cancer that was classified as left-sided compared to patients who received mFOLFOX6, a standard chemotherapy regimen, plus bevacizumab (Avastin®), a monoclonal antibody, according to a finding that will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
The use of trastuzumab deruxtecan (Enhertu®), a new HER2-targeting antibody-drug conjugate, doubled progression-free survival compared to standard-of-care treatment with conventional chemotherapy. It also significantly improved overall survival for patients with metastatic breast cancers expressing low levels of the HER2 receptor, regardless of hormone receptor status. These practice-changing findings identify a new subset of breast cancer - called HER2-low - and redefine how a large proportion of metastatic patients will be treated. This new research will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
Use of high-dose ifosfamide (Ifex®) was found to be superior for treating recurrent and primary refractory Ewing sarcoma compared to three other standard-of-care treatments that are used for the disease, according to research that will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
The use of autologous stem cell transplant (ASCT) early in the course of treatment showed a significant 21.4-month gain in median progression-free survival in younger, newly diagnosed multiple myeloma patients compared to patients who received chemotherapy without an initial transplant. No overall survival benefit has yet been seen using ASCT early compared to keeping it in reserve.
In a collaboration announced on June 4, ASCO will work with the World Health Organization (WHO) to measure and improve the quality of cancer care internationally. The goal is to achieve health-related targets of the U.N. Sustainable Development Goals and WHO Global Action Plan on Non-Communicable Diseases and help cancer professionals provide the best possible care to their patients.
In patients with stage II colon cancer, for which cancer DNA was not present in the blood (circulating tumor DNA, or ctDNA) post-surgical chemotherapy could be skipped without compromising recurrence-free survival. Conversely, for patients where ctDNA was present after surgery, the rate of recurrence among those who received chemotherapy was low, suggesting a survival benefit from post-surgical chemotherapy, according to new research to be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
The use of sacituzumab govitecan (Trodelvy®) an antibody-drug conjugate, resulted in longer progression-free survival compared to physician’s choice of chemotherapy in patients who have received many prior therapies and who had hormone-receptor positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer, according to new research to be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
Ibrutinib (Imbruvica™) combined with bendamustine-rituximab improved progression-free survival by 50% for older patients with newly diagnosed mantle cell lymphoma compared to patients who received a placebo plus bendamustine-rituximab, according to new research that will be reported at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
The addition of nimotuzumab to gemcitabine (Gemzar®) increases overall survival in patients with K-Ras wild-type advanced pancreatic cancer, particularly for patients who did not need surgery for obstruction of a pancreatic bile duct, according to new research to be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.
With the rapid acceleration of the spread of the COVID-19 virus in the United States in March 2020, telemedicine visits became more common for cancer care. However, in an evaluation of telemedicine inequities in 21 common cancers, there were distinctly lower levels of telemedicine use by Black patients and those who were uninsured, lived in suburban or rural areas, and resided in a neighborhood with low socioeconomic status. The research will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.